Toxicity of 13C-labeled linoleic and linolenic acids for diagnostic breath tests
نویسندگان
چکیده
منابع مشابه
Interpretation of non-invasive breath tests using 13C-labeled substrates - a preliminary report with 13C-methacetin
Non-invasive breath tests can serve as valuable diagnostic tools in medicine as they can determine particular enzymatic and metabolic functions in vivo. However, methodological pitfalls have limited the actual clinical application of those tests till today. A major challenge of non-invasive breath tests has remained the provision of individually reliable test results. To overcome these limitati...
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15 صفحه اولThe future of 13C-breath tests.
13C-breath tests are widely applied as a tool to investigate metabolic processes and infectious diseases, but most of them have not yet entered into clinical practice. In order to promote the introduction of more 13C-breath tests into clinical routine application we evaluated the tests so far known with respect to some reasonable criteria, which are valued by one of three marks. The sum sigma o...
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Breath tests are non-invasive, non-radioactive, safe, simple and effective tests able to determine significant metabolic alterations due to specific diseases or lack of specific enzymes. Carbon isotope (13)C, the stable-non radioactive isotope of carbon, is the most used substrate in breath testing, in which (13)C/(12)C ratio is measured and expressed as a delta value, a differences between rea...
متن کامل13C-breath tests for clinical investigation of liver mitochondrial function.
BACKGROUND Mitochondria play a major role in cell energetic metabolism; therefore, mitochondrial dysfunction inevitably participates in or even determines the onset and progression of chronic liver diseases. The assessment of mitochondrial function in vivo, by providing more insight into the pathogenesis of liver diseases, would be a helpful tool to study specific hepatic functions and to devel...
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ژورنال
عنوان ژورنال: Bulletin of Russian State Medical University
سال: 2019
ISSN: 2542-1204,2500-1094
DOI: 10.24075/brsmu.2019.044